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W-5

Calmodulin inhibitor
 
BML-CA315-0020 20 mg 146.00 USD
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Replaces Prod. #: ALX-270-151

Binds to calmodulin, inhibiting Ca2+-calmodulin-regulated enzyme activity. Cell permeable.

Product Specification

Alternative Name:N-(6-Aminohexyl)-1-naphthalenesulfonamide . HCl
 
Formula:C16H22N2O2S . HCl
 
MW:342.9
 
CAS:61714-25-8
 
Purity:≥98% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in water, DMSO (20mg/ml), 100% ethanol (hot) or methanol (hot).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Use/Stability:Stable for at least 1 year after receipt when stored at room temperature. Stock solutions are stable for for up to 6 months at -20°C.
 
Handling:Protect from light.
 
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Product Literature References

N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation : H. Hidaka, et al.; PNAS 78, 4354 (1981), Abstract; Full Text
[Pharmacology of calmodulin: calmodulin antagonist (author's transl)]: H. Hidaka; Prot. Nucl. Acid Enz. 26 , 977 (1981), Abstract;
Hydrophobic regions function in calmodulin-enzyme(s) interactions.: T. Tanaka & H. Hidaka ; J. Biol. Chem. 255, 11078 (1980), Abstract; Full Text

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For Research Use Only. Not for use in diagnostic procedures.
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