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E6 Berbamine

Calmodulin inhibitor
 
BML-CA302-0010 10 mg 109.00 USD
 
BML-CA302-0050 50 mg 448.00 USD
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A potent, selective, cell-permeable calmodulin antagonist. It inhibits calmodulin-dependent enzymes such as MLC kinase (IC50=8 µM) and phosphodiesterase I (IC50=0.53 µM).

Product Specification

Formula:C44H43N3O9
 
MW:757.8
 
CAS:73885-53-7
 
Purity:≥98% (TLC)
 
Appearance:Yellow solid.
 
Solubility:Soluble in DMSO (25 mg/ml) or ethanol (25 mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
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Product Literature References

Interleukin-1β processing is dependent upon a calcium-mediated interaction with calmodulin: J.S. Ainscough, et al.; J. Biol. Chem. 290, 31151 (2015), Application(s): Cell culture, Abstract; Full Text
Interaction of berbamine compound E6 and calmodulin-dependent myosin light chain kinase: Z.-Y. Hu, et al.; Biochem. Pharmacol. 44, 1543 (1992), Abstract;

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Calmodulin
MLCK
PDE
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Calmodulin Inhibitor
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