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Gabapentin

Ca2+ channel blocker
 
BML-CA234-0020 20 mg 74.00 USD
 
BML-CA234-0100 100 mg 307.00 USD
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Gabapentin is a GABA analog which does not act at GABA receptors but which inhibits L-type calcium channels via binding to the α2-δ subunit and neuropathic pain relieving actions. Ligands acting at the α2-δ subunit lead to anticonvulsant, anxiolytic and neuropathic pain-relieving actions.

Product Specification

Formula:C9H17NO2
 
MW:171.2
 
CAS:60142-96-3
 
Purity:≥98% (HPLC)
 
Appearance:White solid.
 
Solubility:Soluble in water.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
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Product Literature References

The mechanism of action of gabapentin in neuropathic pain: J. K. Baillie, et al.; Curr. Opin. Investig. Drugs 7, 33 (2006), Abstract;
Novel cyclopropyl beta-amino acid analogues of pregabalin and gabapentin that target the alpha2-delta protein: J. B. Schwartz, et al. ; J. Med. Chem. 48, 3026 (2005), Abstract;
Mechanism of action of alpha2delta ligands: voltage sensitive calcium channel (VSCC) modulators: S. M. Stahl, et al.; J. Clin. Psychiatry 65, 1033 (2004), Abstract;

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