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AMG-9810

TRPV1 antagonist
 
BML-CA232-0010 10 mg 88.00 USD
 
BML-CA232-0050 50 mg 367.00 USD
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AMG-9810 is an antagonist of capsaicin activation of TRPV1 (IC50=24.5 nM) as well as activation by acid, heat, and endogenous ligands.

Product Specification

Formula:C21H23NO3
 
MW:337.4
 
CAS:545395-94-6
 
Purity:≥98%
 
Appearance:Off-white solid.
 
Solubility:Soluble in DMSO (>25mg/ml); ethanol (20mg/ml).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
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Product Literature References

AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties: N. R. Gavva, et al.; J. Pharmacol. Exp. Ther. 313, 474 (2005), Abstract; Full Text

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