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Isradipine

Ca2+ channel blocker
 
BML-CA213-0010 10 mg 88.00 USD
 
BML-CA213-0050 50 mg 336.00 USD
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Potent and selective L-type calcium channel blocker. A clinically useful antihypertensive agent which has anti-atherosclerotic effects and improves endothelium-mediated NO-dependent vasodilation. Displays neuroprotective activity in a rat model of focal ischemia.

Product Specification

Formula:C19H21N3O5
 
MW:371.4
 
CAS:75695-93-1
 
RTECS:U57968632
 
Purity:≥98% (HPLC)
 
Appearance:Yellow solid.
 
Solubility:Soluble in DMSO (25 mg/ml) or 100% ethanol (15 mg/ml).
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Handling:Protect from light. Store under inert gas.
 
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Product Literature References

Isradipine improves endothelium-dependent vasodilation in normotensive coronary artery disease patients with hypercholesterolemia: C. Bracht, et al.; J. Hyperten. 19, 899 (2001), Abstract;
Use of diffusion-weighted MRI and neurological deficit scores to demonstrate beneficial effects of isradipine in a rat model of focal ischemia: S. Chandra, et al.; Pharmacology 58, 292 (1999), Abstract;

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