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Bz-Val-Gly-Arg-AMC

 
BML-BW9375-0005 5 mg 112.00 USD
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A substrate for the trypsin-like activity of the 20S proteasome.

Product Specification

Alternative Name:Bz-VGR-AMC
 
Sequence:Bz-VGR-AMC, Fluorogenic Substrate
 
Formula:C30H37N7O6 . TFA
 
MW:591.67
 
CAS:87779-49-5
 
Purity:≥98% (HPLC)
 
Appearance:White powder.
 
Solubility:Soluble in methanol or DMSO.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 

Product Literature References

Skeletal Muscle Denervation Investigations: Selecting an Experimental Control Wisely: H. Liu, et al.; Am. J. Physiol. Cell Physiol. (2019), Abstract;
Agouti Related Peptide Secreted Via Human Mesenchymal Stem Cells Upregulates Proteasome Activity in an Alzheimer's Disease Model: N.K. Lee, et al.; Sci. Rep. 7, 39340 (2017), Abstract; Full Text
Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases: L. Lauinger, et al.; Nat. Chem. Biol. 13, 709 (2017), Abstract; Full Text
Denervation-Induced Activation of the Standard Proteasome and Immunoproteasome: H.M. Lee, et al.; PLoS One 11, e0166831 (2016), Abstract; Full Text
Pim1 inhibition as a novel therapeutic strategy for Alzheimer’s disease: R. Velazquez, et al.; Mol. Neurodegener. 11, 52 (2016), Application(s): Proteasome activity, brain homogenate, Abstract; Full Text
Marchantin M: a novel inhibitor of proteasome induces autophagic cell death in prostate cancer cells: H. Jiang, et al.; Cell Death Dis. 4, e761 (2013), Application(s): Fluorogenic substrate for kinetics assay of 20S proteasome, Abstract; Full Text

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