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Ethyl β-carboline-3-carboxylate

Benzodiazepine receptor ligand
 
BML-B102-0500 500 mg 130.00 USD
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Benzodiazepine inverse agonist. Antagonizes some of the actions of benzodiazepines in vivo. Lowers seizure threshold and reverses the sedative effect of flurazepam. Anxiogenic and convulsant activity. SAR studies.

Product Specification

Formula:C14H12N2O2
 
MW:240.3
 
CAS:74214-62-3
 
Purity:≥97% (TLC)
 
Identity:Determined by IR.
 
Appearance:Pale yellow solid.
 
Solubility:Soluble in ethanol or DMSO.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
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Product Literature References

Anxiogenic and non-anxiogenic benzodiazepine antagonists: L. Prado de Carvalho, et al.; Nature 301, 64 (1983), Abstract;
Beta-carbolines: synthesis and neurochemical and pharmacological actions on brain benzodiazepine receptors: M. Cain, et al.; J. Med. Chem. 25, 1081 (1982), Abstract;
Ethyl beta-carboline carboxylate lowers seizure threshold and antagonizes flurazepam-induced sedation in rats: P. J. Cowan, et al.; Nature 290, 54 (1981), Abstract;

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