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Ac-Gly-Pro-Leu-Asp-AMC

 
BML-AW9560-0005 5 mg 717.00 USD
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Highly specific substrate for the caspase-like peptidic activity of the 20S proteasome.

Product Specification

Alternative Name:Ac-GPLD-AMC
 
Sequence:Ac-GPLD-AMC, Fluorogenic Substrate
 
Formula:C29H37N5O9
 
MW:599.64
 
Source:Synthetic.
 
Purity:≥98% (HPLC)
 
Appearance:White solid.
 
Solubility:Soluble in 20% aqueous acetic acid (1mg/ml).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Store solutions at or below -20°C for up to 3 months
 

Product Literature References

Bortezomib Amplifies Effect on Intracellular Proteasomes by Changing Proteasome Structure: D.S. Pitcher, et al.; EBioMedicine 2, 642 (2015), Application(s): Fluorescence, Abstract;
The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites: A. F. Kisselev, et al.; J Biol. Chem. 278, 35869 (2003), Abstract; Full Text

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Proteasome 20S
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