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Guanfacine . HCl

Adrenergic receptor ligand
 
BML-AR102-0100 100 mg 69.00 USD
 
BML-AR102-0500 500 mg 274.00 USD
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Centrally acting α2-adrenergic receptor agonist. In the guinea pig cerebral cortex, the Kd is 20 and 880 nM for the α2A- and the α2C-adrenoceptor, respectively. Antihypertensive agent.

Product Specification

Formula:C9H9Cl2N3O . HCl
 
MW:282.5
 
CAS:29520-14-7 / 29110-48-3
 
Purity:≥99% (TLC)
 
Identity:Determined by NMR.
 
Appearance:White solid.
 
Solubility:Soluble in water (25 mg/ml).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
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Product Literature References

From alpha and beta to I1: an overview of sympathetic receptors involved in blood pressure control targets for drug treatment: P. A. van Zweiten, et al.; J. Cardiovasc. Pharmacol. 27, S5 (1996), Abstract;
Comparison of the binding activities of some drugs on alpha 2A, alpha 2B and alpha 2C-adrenoceptors and non-adrenergic imidazoline sites in the guinea pig: S. Uhlen, et al.; Pharmacol. Toxicol. 76, 353 (1995), Abstract;

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