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(+/-)Cyanopindolol hemifumarate

Adrenergic receptor and serotonin receptor antagonist
 
BML-AR101-0010 10 mg 100.00 USD
 
BML-AR101-0050 50 mg 321.00 USD
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ß-Adrenergic receptor antagonist. Serotonin 5HT1A/1B antagonist.

Product Specification

Formula:C16H21N3O2 . 1/2C4H4O4
 
MW:345.4
 
CAS:69906-85-0
 
Purity:≥99% (TLC)
 
Appearance:White solid.
 
Solubility:Soluble in warm water (2 mg/ml), DMSO (8 mg/ml).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Use/Stability:Store solutions at -20°C for up to 4 months
 
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Product Literature References

Comparison of the profiles of agonists as stimulants of the beta 3-adrenoceptor in vitro with their gastroprotective effects in the conscious rat: A. K. Bahl, et al.; Br. J. Pharmacol. 117, 580 (1996), Abstract; Full Text
Characterization of 5-hydroxytryptamine receptors in goat cerebral arteries: F. J. Miranda, et al.; Gen. Pharmacol. 26, 1267 (1995), Abstract;
Blockade of the central 5-HT autoreceptor by beta-adrenoceptor antagonists: D. N. Middlemiss, et al.; Eur. J. Pharmacol. 120, 51 (1986), Abstract;
Cyanopindolol is a highly potent and selective antagonist at the presynaptic serotonin autoreceptor in the rat brain cortex: E. Schlicker, et al.; Naunyn. Schmied. Arch. Pharmacol. 331, 398 (1985), Abstract;
Specificity of the beta 2-adrenergic receptor stimulating cyclic AMP accumulation in the intermediate lobe of rat pituitary gland: H. Meunier & F. Labrie ; Eur. J. Pharmacol. 81, 411 (1982), Abstract;

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