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Bopindolol malonate

Adrenergic receptor ligand
 
BML-AR100-0100 100 mg 67.00 USD
 
BML-AR100-0500 500 mg 266.00 USD
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A slowly dissociating β1-adrenergic receptor antagonist. Antihypertensive. Antioxidant (IC50=1.8 µM) and free radical scavenging activity.

Product Specification

Formula:C23H28N2O3 . C3H4O4
 
MW:484.6
 
CAS:82857-38-3
 
Purity:≥97% (HPLC)
 
Appearance:White solid.
 
Solubility:Soluble in water at 3mg/ml.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Use/Stability:Store solutions at -20°C for up to 4 months
 
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Product Literature References

Alpha-1 and beta-adrenergic receptor blocking potencies of bopindolol and its two metabolites (18-502 and 20-785) as assessed by radioligand binding assay methods: Y. Hosohata, et al.; Gen. Pharmacol. 26, 743 (1995), Abstract;
Antioxidative action of the beta-adrenoceptor antagonist bopindolol and its metabolite 18-502: Y. Aniya, et al.; Jpn. J. Pharmacol. 68, 323 (1995), Abstract; Full Text
Bopindolol is a slowly dissociating beta 1-adrenoceptor antagonist when compared to other beta-blockers: Y. Hosohata, et al.; Biol. Pharm. Bull. 18, 1066 (1995), Abstract;
The affinity of bopindolol and its two metabolites for a beta 2-adrenoceptor in the bovine mesenteric artery: Y. Hosohata, et al.; Biol. Pharm. Bull. 17, 1296 (1994), Abstract;

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