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CV-Cathepsin L detection kit

BML-AK127-0001 1 Kit 344.00 USD
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Elevated cathepsin enzyme activity often indicates the presence of a pathological condition including cancer, Alzheimer's disease, autoimmune disease, and osteoporosis. Based on the dye cresyl violet and the cathepsin L PheArg peptide recognition sequence, this kit allows the detection of cathepsin L activity in living cells by fluorescence microscopy. Once cells are grown, staining is completed in just a few minutes. Hoechst 33342 stain and Acridine Orange are also included to allow visualization of nuclei and lysosomes.
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Product Specification

Applications:Fluorescence microscopy, Fluorescent detection
Shipping:Shipped on Blue Ice
Long Term Storage:+4°C
Contents:CV-(FR)2 reagent, Acridine Orange, Hoechst 33342 stain.
UniProt ID:P07711 (cathepsin L1), O60911 (cathepsin L2)

Product Literature References

Defective Autophagy in Diabetic Retinopathy: J.M. Lopes de Faria, et al.; Invest. Ophthalmol. Vis. Sci. 57, 4356 (2016), Application(s): Activity measurement of cathepsin L and D, Rat retinal MCs, Abstract; Full Text

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