Elevated cathepsin enzyme activity often indicates the presence of a pathological condition including cancer, Alzheimer's disease, autoimmune disease, and osteoporosis. Based on the dye cresyl violet and the cathepsin L PheArg peptide recognition sequence, this kit allows the detection of cathepsin L activity in living cells by fluorescence microscopy. Once cells are grown, staining is completed in just a few minutes. Hoechst 33342 stain and Acridine Orange are also included to allow visualization of nuclei and lysosomes.
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Product Details
| Applications: | Fluorescence microscopy, Fluorescent detection
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| Shipping: | Blue Ice |
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| Long Term Storage: | +4°C |
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| Contents: | CV-(FR)2 reagent, Acridine Orange, Hoechst 33342 stain. |
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| UniProt ID: | P07711 (cathepsin L1), O60911 (cathepsin L2) |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Defective Autophagy in Diabetic Retinopathy: J.M. Lopes de Faria, et al.; Invest. Ophthalmol. Vis. Sci.
57, 4356 (2016),
Application(s): Activity measurement of cathepsin L and D, Rat retinal MCs,
Abstract;
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