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MMP Inhibitor profiling kit, fluorometric

BML-AK016-0001 96 wells 970.00 USD
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A QUANTIZYME® Assay System Complete assay system designed to examine the specificity of inhibitors against a panel of ten matrix metalloproteinase enzymes. The assays are performed in a convenient 96-well microplate format using a sensitive fluorogenic substrate . Included are active MMP enzymes, assay buffer, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet.

Product Specification

Applications:Fluorescent detection, HTS
Activity assay
Shipping:Shipped on Dry Ice
Long Term Storage:-80°C

Product Literature References

Inhibitory effects of dried longan (Euphoria longana Lam.) seed extract on invasion and matrix metalloproteinases of colon cancer cells: A. Panyathep, et al.; J. Agric. Food Chem. 61, 3631 (2013), Abstract;
Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer: T. Fujisawa, et al.; PLoS One 7, e34437 (2012), Application(s): IC50 of cysteamine and batimastat, Abstract; Full Text
Development and validation of novel enzyme activity methods to assess inhibition of matrix metalloproteinases (MMPs) in human serum by antibodies against enzyme therapeutics: T.J. Edkins, et al.; J. Pharm. Biomed. Anal. 70, 408 (2012), Abstract;
Potent "clicked" MMP2 inhibitors: synthesis, molecular modeling and biological exploration: J.M. Zapico, et al.; Org. Biomol. Chem. 9, 4587 (2011), Abstract;

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