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PD 116,948

Adenosine receptor ligand
 
BML-AD100-0020 20 mg 62.00 USD
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Potent and selective adenosine A1 receptor antagonist.

Product Specification

Alternative Name:8-Cyclopentyl-1,3-dipropylxanthine
 
Formula:C16H24N4O2
 
MW:304.4
 
CAS:102146-07-6
 
Purity:≥98% (TLC)
 
Identity:Determined by 1H-NMR and MS.
 
Appearance:White solid.
 
Solubility:Soluble in 100% ethanol (25mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
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Product Literature References

Identification and functional characterization of A1 and A2 adenosine receptors in the rat vas deferens: a comparison with A1 receptors in guinea pig left atrium and A2 receptors in guinea pig aorta: P. L. Martin & J. M. May; J. Pharmacol. Exp. Ther. 269, 1228 (1994), Abstract;
A selective adenosine antagonist (8-cyclopentyl-1,3-dipropylxanthine) eliminates both neuromuscular depression and the action of exogenous adenosine by an effect on A1 receptors: R. A. Redman & E. M. Silinsky; Mol. Pharmacol. 44, 835 (1993), Abstract;
Effect of the selective A1 adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine on acute renal dysfunction induced by Escherichia coli endotoxin in rats: R.J. Knight, et al.; J. Pharm. Pharmacol. 45, 979 (1993), Abstract;
PD 116,948, a highly selective A1 adenosine receptor antagonist: S. J. Haleen, et al.; Life Sci. 40, 555 (1987), Abstract;

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