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Puromycin Aminonucleoside

Puromycin analog that does not inhibit protein synthesis
 
BML-A260-0050 50 mg 209.00 USD
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Replaces Prod. #: ALX-480-083

A puromycin analog which does not inhibit protein synthesis or induce apoptosis. It is a glomerular epithelial cell toxin which may be used to induce nephropathy in laboratory animals.

Product Specification

Alternative Name:3'-Amino-3'-Deoxy-N,N-dimethyladenosine
 
Formula:C12H16N6O3
 
MW:294.3
 
CAS:58-60-6
 
Purity:≥98% (TLC)
 
Appearance:White solid.
 
MeltingPoint:222-223°C
 
Solubility:Soluble in water (10mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
bml-a260
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bml-a260

Product Literature References

Puromycin aminonucleoside suppresses integrin expression in cultured glomerular epithelial cells: U. Krishnamurti et al.; J. Am. Soc. Nephrol. 12, 758 (2001), Abstract;
Dietary vitamin E supplementation ameliorates renal injury in chronic puromycin aminonucleoside nephropathy: H. Trachtman et al.; J. Am. Soc. Nephrol. 5, 1811 (1995), Abstract;
Reevaluation of the role of de novo protein synthesis in rat thymocyte apoptosis: S.C. Chow et al.; Exp Cell Res 216, 1995 (1995), Abstract;

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