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SCREEN-WELL® Natural Product library

BML-2865-0500 1 Library 500 µl/well Inquire for pricing
BML-2865-0100 1 Library 100 µl/well Inquire for pricing
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Natural products are an unsurpassed source of chemical diversity and an ideal starting point for any screening program for pharmacologically active small molecules. Historically, natural products have been the most successful source of new drugs. The SCREEN-WELL® Natural Product library offers over 500 isolated natural compounds of known structure and includes many compounds from ethnopharmacology. Compounds are provided in solution in DMSO. Individual compounds or subsets can be resupplied in gram quantities.

Product Specification

Kit/Set Contains:502 compounds including compounds from the following classes of products: Terpenoids, Peptolides, Flavones, Coumarins, Alkaloids, Macrolides, Isoflavones, Synthetic derivates and many more.
Concentration:2mg/ml in DMSO
Use/Stability:Stable for at least one year from the date of receipt when stored at -80°C.
Shipping:Shipped on Dry Ice
Long Term Storage:-80°C
Technical Info/Product Notes:

Application Note: High Throughput Screening Applications.

Product Literature References

Cyclopiazonic acid, an inhibitor of calcium-dependent ATPases with antiviral activity against human respiratory syncytial virus: R. Cui, et al.; Antiviral Res. 132, 38 (2016), Abstract;
Targeting human respiratory syncytial virus transcription anti-termination factor M2-1 to inhibit in vivo viral replication: B. Bailly, et al.; Sci. Rep. 6, 25806 (2016), Application(s): Cell culture, Abstract; Full Text
Phenotypic screening identifies protein synthesis inhibitors as H-ras-nanocluster increasing tumor growth inducers: A.K. Najumudeen, et al.; Biochemistry 54, 7212 (2015), Application(s): Chemical screening with H-ras-NANOPS, Abstract;
High-throughput screen of natural product libraries for hsp90 inhibitors: J. Davenport, et al.; Biology (Basel) 3, 101 (2014), Application(s): HTS for HSP90 inhibitors, Abstract; Full Text
Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors: H. Venkannagari, et al.; Eur. J. Pharm. Sci. 49, 148 (2013), Abstract;
Inhibition of Chikungunya Virus Replication by Harringtonine, a Novel Antiviral That Suppresses Viral Protein Expression: P. Kaur, et al.; Antimicrob. Agents Chemother. 57, 155 (2013), Abstract; Full Text
Natural compounds inhibiting the replication of Porcine reproductive and respiratory syndrome virus: A.K. Karuppannan, et al.; Antiviral Res. 94, 188 (2012), Abstract;
Gambogic acid, a natural product inhibitor of Hsp90: J. Davenport, et al.; J. Nat. Prod. 74, 1085 (2011), Abstract;

General Literature References

Unconventional natural sources for future drug discovery: M. Tulp et al.; Drug Discov Today 9, 450 (2004), Abstract;
Natural products as sources of new drugs over the period 1981-2002: D. J. Newman et al.; J Nat Prod 66, 7 (2003), Abstract;
Ethnopharmacology in drug discovery: an analysis of its role and potential contribution: M. Heinrich et al.; J. Pharm. Pharmacol. 53, 425 (2001), Abstract;
Strategies for discovering drugs from previously unexplored natural products: A. Harvey et al.; Virology 5, 294 (2000), Abstract;

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