United States
FDA approved drug library
Accelerates drug optimization with compounds of known safety and bioavailability
| BML-2841-0500 | 1 Library | 500 µl/well | INQUIRE | ||
| BML-2841-0100 | 1 Library | 100 µl/well | INQUIRE | ||
Screening FDA-approved drugs accelerates drug discovery:
· 100% known bioactivity
· Greatest degree of drug-likeness available
· Known safety & bioavailability
· Accelerates drug optimization
Drug repositioning or repurposing can be an important part of any drug discovery program and has led to several blockbuster drugs (e.g. Viagra and Rogaine). High-content screens, new biomarkers and noninvasive imaging techniques have created new opportunities for pursuing novel indications for approved compounds.
· 100% known bioactivity
· Greatest degree of drug-likeness available
· Known safety & bioavailability
· Accelerates drug optimization
Drug repositioning or repurposing can be an important part of any drug discovery program and has led to several blockbuster drugs (e.g. Viagra and Rogaine). High-content screens, new biomarkers and noninvasive imaging techniques have created new opportunities for pursuing novel indications for approved compounds.
Product Specification
| Quantity: | 100µl or 500µl per well |
| Concentration: | DMSO solutions (2 mg/ml) |
| Long Term Storage: | -80°C |
| Kit/Set Contains: | 640 compounds, selected to maximize chemical and pharmacological diversity |
| Background / Technical Information: |  |
Product Literature References
A chemical screening system for glucocorticoid stress hormone signaling in an intact vertebrate: B.D. Weger, et al.; ACS Chem. Biol. 7, 1178 (2012), Application(s): Treatment of zebrafish cells and larvae, Abstract; Full Text
Fish in a dish: drug discovery for hearing habilitation: R. Esterberg, et al.; Drug Discov. Today Epub ahead of print, (2012), Abstract;
A Bioluminogenic HDAC Activity Assay: Validation and Screening: F. Halley et al.; J. Biomol. Screen. Epub ahead of print, DOI: 10.1177/1087057111416004 (2011), Application, Abstract;
Cell line and drug-dependent effect of ERBB3 on cancer cell proliferation, chemosensitivity, and multidrug actions: B. Chen et al.; Int. J. High Throughput Screen. 1, 49 (2010), Application, Full Text
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