ICCB known bioactives library
| BML-2840-0100 | 1 Library | 100 µl/well | INQUIRE | |
The ICCB Known Bioactives Library is an important new product for use in chemical genetics and drug discovery. The library is a collection of 480 diverse biologically active compounds with defined biological activity and was developed in collaboration with the Harvard Institute of Chemistry and Cell Biology. It includes the following classes of compounds: GPCR ligands, Second messenger modulators, Nuclear receptor ligands, Actin & tubulin modulators, Kinase inhibitors, Protease inhibitors, Ion channel blockers, Gene regulation agents, Lipid biosynthesis inhibitors, many other classes.
Product Specification
| Concentration: | DMSO solutions (concentration vary by compound and are provided in the documentation) |
| Quantity: | 100µl per well |
| Kit/Set Contains: | 480 compounds. Includes compounds that affect most cellular processes and drug targer classes, including: GPCR ligands, Second messenger modulators, Nuclear receptor ligands, Actin and tubulin modulators, Kinase inhibitors, Protease inhibitors, Ion channel blockers, Gene regulation agents, Lipid biosynthesis inhibitors, Phosphodiesterase inhibitors, and many other classes. |
| Shipping: | SHIPPED ON DRY ICE |
| Long Term Storage: | -80°C |
| Background / Technical Information: | Please click here for the comprehensive product data sheet. |
General Literature References
Scaffold composition and biological relevance of screening libraries A. Shelat et al. Nat. Chem. Biol. 3 442 (2007) Abstract
Small molecule regulators of autophagy identified by an image-based high-throughput screen L. Zhang et al. Proc. Natl. Acad. Sci. USA 104 19023 (2007) Abstract
Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein H. Pan et al. J. Biol. Chem. 283 33808 (2008) Abstract
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27-Mar-09 |
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