The ICCB Known Bioactives Library is an important new product for use in chemical genetics and drug discovery. The library is a collection of 480 diverse biologically active compounds with defined biological activity and was developed in collaboration with the Harvard Institute of Chemistry and Cell Biology. It includes the following classes of compounds: GPCR ligands, Second messenger modulators, Nuclear receptor ligands, Actin & tubulin modulators, Kinase inhibitors, Protease inhibitors, Ion channel blockers, Gene regulation agents, Lipid biosynthesis inhibitors, many other classes. Each compound is supplied dissolved in DMSO at 100 µL and is ready for assaying. The library can be used for assay development and validation, mechanism profiling, lead screening or as a reference library.
Contact compoundlibraries@enzolifesciences.com for a complete list of compounds in the library.