The SCREEN-WELL®Protease Inhibitor Library includes 53 known protease inhibitors on a single 96-well plate. Inhibitors are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well plates at either 100 or 500 microliters per well. The library includes inhibitors to a broad range of important proteases and is a convenient and cost-effective way to purchase a panel of protease inhibitors for chemical genomics, assay development, and other applications. It includes inhibitors of: Calpains, TPPII, Neutrophil Elastase, Cathepsins, DPPIV, Caspases, Granzyme B, γ-Secretase, Furin, MMPs, ACE, Kallikrein, Proteasome, Aminopeptidase B, and many more.
Product Details
| Applications: | HTS
|
| |
| Use/Stability: | Stable for at least one year from the date of receipt when stored at -80°C. |
| |
| Shipping: | Dry Ice |
| |
| Long Term Storage: | -80°C |
| |
| Technical Info/Product Notes: |  |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Product Literature References
BML-265 and tyrphostin AG1478 disperse the Golgi apparatus and abolish protein transport in human cells: G. Boncompain, et al.; Front. Cell. Dev. Biol.
7, 232 (2019),
Abstract;
Full Text
Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma: U.I. Scholl, et al.; J. Clin. Invest.
127, 2739 (2017),
Abstract;
Full Text
Screening for small molecule inhibitors of statin-induced APP C-terminal toxic fragment production: K.S. Poksay, et al.; Front. Pharmacol.
8, 46 (2017),
Abstract;
Full Text
Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury: S. Martens, et al.; Cell Death Dis.
8, e2904 (2017),
Abstract;
Full Text
Microplate fluorescence protease assays test the inhibition of select North American snake venoms' activities with an anti-proteinase library: J. A. Price; Toxicon
103, 145 (2015),
Application(s): Protease Assay,
Abstract;
PRL-3 mediates the protein maturation of ULBP2 by regulating the tyrosine phosphorylation of HSP60: W.H. Leung, et al.; J. Immunol.
194, 2930 (2015),
Abstract;
Full Text
SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds: H.H. Cheung et al.; Cell Death Dis.
2, e146 (2011),
Abstract;
