Orphan ligand library



BML-2825-0500	1 Library	500 µl/well	INQUIRE

The Screen-Well^TM Orphan ligand library contains 84 compounds with defined, putative, potential or speculative biological activity but whose protein binding partners have not been identified. Ligands are supplied dissolved in biocompatible solvents at 10mM and aliquoted into a deep-well plate at 500µl per well. The library is a rich source of ligands for receptor de-orphaning. Includes the following classes of ligands: Trace Amines, Neurotransmitter Metabolites, Endogenous β-carbolines, Urinary Metabolites, Nicotine Congeners, D-Amino Acids.

Quantity:	84 compounds, 500μl per compound

Long Term Storage:	-80°C

Background / Technical Information:	Please click here for the comprehensive product data sheet.

Product Literature References

A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators: P. Stoilov et al.; Proc. Natl. Acad. Sci. USA 105, 11218 (2008), Application, Abstract;

A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation: J. P. Saxe; Chem. Biol. 14, 1019 (2007), Abstract;

General Literature References

Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay: H. Yin, et al.; J. Biol. Chem. 284, 12328 (2009), Abstract;