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| BML-2825-0500 |
1 Library |
500 µl/well |
INQUIRE |
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The Screen-Well
TM Orphan ligand library contains 84 compounds with defined, putative, potential or speculative biological activity but whose protein binding partners have not been identified. Ligands are supplied dissolved in biocompatible solvents at 10mM and aliquoted into a deep-well plate at 500 µl per well. The library is a rich source of ligands for receptor de-orphaning. Includes the following classes of ligands: Trace Amines, Neurotransmitter Metabolites, Endogenous ß-carbolines, Urinary Metabolites, Nicotine Congeners, D-Amino Acids.
Receptors for endogenous trace amines have recently been deorphanized. Endogenous ß-carbolines have been shown to display varied biological effects such as hallucinations, hypotension and others. Nicotine congeners such as nornicotine are biologically active and may act at novel nicotinic receptor subtypes.Contact
compoundlibraries@enzolifesciences.com for a complete list of compounds in the library.
For details on the terms of use of this product, click here.
Product Specification
General Literature References
Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay H. Yin, et al. J. Biol. Chem. 284 12328 (2009)
Abstract