Product Specification
| Alternative Name: | Tazarotene-induced gene 2, RAR-responsive protein, RARRES2, Retinoic acid receptor responder protein 2, TIG2 |
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| Sensitivity: | 0.1ng/ml (range 0.156 to 10ng/ml). |
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| Kit/Set Contains: | 1 vial Standard (lyophilized) (STD).1 vial Coating Antibody (COAT).1 vial Detection Antibody (DET). |
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| Application: | For the quantitative determination of human chemerin from biological fluids (serum, plasma and cell culture supernatant). |
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| Short Term Storage: | +4°C |
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| Handling: | Avoid freeze/thaw cycles. For long term storage keep the standard (STD) at -20°C. |
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| Miscellaneous/General: | Chemerin (tazarotene-induced gene 2; TIG2) is a chemotactic agent that was identified as the ligand for the orphan G protein-coupled receptor ChemR23. chemerin has been shown to be expressed abundantly in adipose tissue and to function as an adipokine [1, 2]. Chemerin potentiates insulin-stimulated glucose uptake and regulates adipogenesis and adipocyte metabolism [1]. |
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General Literature References
Chemerin is a novel adipokine associated with obesity and metabolic syndrome: K. Bozaoglu, et al.; Endocrinology
148, 4687 (2007),
Abstract;
Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism: K.B. Goralski, et al.; J. Biol. Chem.
282, 28175 (2007),
Abstract;
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