Polyclonal antibody prepared against the Adda moiety binds to microcystins and nodularins, allowing the congener-independent determination of these toxins and many of its congeners, and does not cross-react with other non-related toxins or compounds. No pre-sample preparation required. Total time for measurement is less than 2.5 hours. Enables simultaneous measurement of multiple samples at reasonable costs. Patented technology.U.S. Patent No. 6,967,240Worldwide Patent PCT WO 01/18059 A2
Product Specification
| Quantity: | 96 wells (~80 tests) |
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| Sensitivity: | 0.1ng/ml (range 0.15 to 5ng/ml) |
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| Application: | For the quantitative and sensitive congener-independent detection of microcystins and nodularin in water samples. |
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| Long Term Storage: | +4°C |
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| Miscellaneous/General: | Microcystins are extremely toxic compounds produced by cyanobacteria (blue-green algae), belonging to species of Microcystis, Oscillatoria, Anabaena and Nostoc. The contamination of drinking water or water of recreational areas can cause severe health problems to exposed humans and animals. Microcystins possess a cyclic heptapeptide structure of the general composition cyclo(-D-Ala-L-X-D-erythro-β-methylisoAsp-L-Y-Adda-D-iso-Glu-N-methyldehydroAla), where Adda is the unusual C20 aa 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid and X and Y are variable L-aa. |
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Product Literature References
Effect of irrigation with lake water containing microcystins on microcystin content and growth of ryegrass, clover, rape, and lettuce: J.R. Crush, et al.; Environ. Toxicol.
23, 246 (2008),
Abstract;
A review of analytical methods for assessing the public health risk from microcystin in the aquatic environment: P.R. Hawkins, et al.; J. Water Supply 54, 509 (2005),
Congener-independent immunoassay for microcystins and nodularins: W.J. Fischer, et al.; Environ. Sci. Technol.
35, 4849 (2001),
Abstract;