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Caspase inhibitor set III

 
ALX-850-227-KI01 1 Set 504.00 USD
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Synthetic peptides that irreversibly inhibit the activity of each of the caspase-family proteases. YVAD is the recognition sequence for caspase-1/ICE, VDVAD is the recognition sequence for caspase-2, DEVD is the recognition sequence for caspase-3/CPP32, WEHD is the recognition sequence for caspase-5, VEID is the recognition sequence for caspase-6/Mch2, IETD is the recognition sequence for caspase-8/FLICE, LEHD is the recognition sequence for caspase-9, and VAD is the recognition sequence for a caspase(s) that functions upstream of most other caspases.

Product Specification

Recommended Dilutions/Conditions:We recommend using 1,000x dilutions for inhibiting caspase activity in Jurkat cell culture (e.g. add 1µl to 1ml of culture medium). Optimal doses may vary for different cells and culture conditions and must be determined individually.
 
Kit/Set Contains:Contains 25µl (2mM) each of the following inhibitors: 
- Caspase-1 Inhibitor, Z-YVAD-FMK, yellow cap  
- Caspase-2 Inhibitor, Z-VDVAD-FMK, orange cap
- Caspase-3 Inhibitor, Z-DEVD-FMK, red cap  
- Caspase-5 Inhibitor, Z-WEHD-FMK, clear cap  
- Caspase-6 Inhibitor, Z-VEID-FMK, violet cap  
- Caspase-8 Inhibitor, Z-IETD-FMK, green cap  
- Caspase-9 Inhibitor, Z-LEHD-FMK, blue cap  
- Caspase-Family Inhibitor, Z-VAD-FMK, amber cap
 
Formulation:Liquid. In DMSO.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 

Product Literature References

Bortezomib Amplifies Effect on Intracellular Proteasomes by Changing Proteasome Structure: D.S. Pitcher, et al.; EBioMedicine 2, 642 (2015), Application(s): Cell Culture, Abstract;

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