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HLA-E (human) monoclonal antibody (MEM-E/07)

 
ALX-805-709-C100 100 µg 248.00 USD
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Product Specification

Clone:MEM-E/07
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant human HLA-E refolded with β2-microglobulin and peptide.
 
UniProt ID:P13747
 
Species reactivity:Human
 
Specificity:Recognizes native surface-expressed HLA-E, but not denatured heavy chain of HLA-E.
 
Crossreactivity:Cross-reacts with classical MHC Class I molecules HLA-B7 (strongly), -B8 (moderately), -B27, -B44 (weakly).
 
Applications:Flow Cytometry, IP
 
Purity Detail:Protein A-affinity purified.
 
Formulation:Liquid. In PBS, pH 7.4, containing 15mM sodium azide.
 
Use/Stability:Stable for at least 6 months when stored at +4°C.
 
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 

Product Literature References

HLA-E surface expression is independent of the availability of HLA class I signal sequence-derived peptides in human tumor cell lines: G.L. Palmisano, et al.; Hum. Immunol. 66, 1 (2005), Abstract;
Tissue Antigens: L. Sibilio et al.; Abstract 45 from the 3rd Int. Conference on HLA-G, Paris 62, 339 (2003),

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