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CD11a (human) monoclonal antibody (MEM-25)

 
ALX-805-061-C100 100 µg 194.00 USD
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Product Specification

Alternative Name:LFA-1, αL integrin
 
Clone:MEM-25
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Leukocytes from a patient suffering from a LGL-type leukaemia.
 
UniProt ID:P20701
 
Species reactivity:Human
 
Specificity:Recognizes the α subunit (CD11a; αL integrin) of LFA-1.
 
Applications:Flow Cytometry, IP, FUNC
 
Recommended Dilutions/Conditions:Flow Cytometry (2µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Functional Application: blocks binding of CD54 (ICAM-1); suitable for affinity purification of LFA-1 from leukocytes.
 
Purity Detail:Protein A-affinity purified.
 
Formulation:Liquid. In PBS, pH 7.4, containing 15mM (~0.1%) sodium azide.
 
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 

Product Literature References

Roles played by lymphocyte function-associated antigen-1 in the regulation of lymphocytic cholinergic activity.: T. Fujii et al.; Life Sci. 80, 24 (2007), Abstract;
Monoclonal Lym-1 antibody-dependent cytolysis by neutrophils exposed to granulocyte-macrophage colony-stimulating factor: intervention of FcgammaRII (CD32), CD11b-CD18 integrins, and CD66b glycoproteins: L. Ottonello, et al.; Blood 93, 3505 (1999), Abstract; Full Text
Monoclonal antibodies against human leucocyte antigens. IV. Antibodies against subunits of the LFA-1 (CD11a/CD18) leucocyte-adhesion glycoprotein: V. Bazil, et al.; Folia Biol. (Praha) 36, 41 (1990), Abstract;

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