CD83 (human), mAb (1G11)



ALX-805-045-C050	50 µg	176.00 USD

Product Specification

Concentration:	1.9mg/ml

Purity Detail:	Protein G-affinity purified.

Formulation:	Liquid. In PBS containing 0.01% sodium azide.

Clone:	1G11

Isotype:	Rat IgG1

Immunogen:	Recombinant human CD83 (extracellular domain).

Specificity:	Recognizes human CD83. The binding affinity strongly increases after deglycosylation of mature DC.

Application:	Flow Cytometry, Western blot. Not inhibitory to DC mediated T cell stimulation in mixed lymphocyte reactions.

Short Term Storage:	+4°C

Long Term Storage:	-20°C

Handling:	Do not freeze/thaw.

Product Literature References

Overexpression, purification, and biochemical characterization of the extracellular human CD83 domain and generation of monoclonal antibodies: M. Lechmann, et al.; Protein Exp. Purif. 24, 445 (2002), Abstract;

The extracellular domain of CD83 inhibits dendritic cell-mediated T cell stimulation and binds to a ligand on dendritic cells: M. Lechmann, et al.; J. Exp. Med. 194, 1813 (2001), Abstract; Full Text