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CD83 (human) monoclonal antibody (4B5)

 
ALX-805-044-C050 50 µg 180.00 USD
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Product Specification

Clone:4B5
 
Host:Rat
 
Isotype:IgG2a
 
Immunogen:Recombinant human CD83 (extracellular domain).
 
UniProt ID:Q01151
 
Species reactivity:Human
 
Specificity:Deglycosylated CD83 is only weakly recognized.
 
Applications:Flow Cytometry, WB
 
Application Notes:NOT inhibitory to DC mediated T cell stimulation in mixed lymphocyte reactions.
 
Formulation:Liquid. Protein G purified antibody in PBS containing 0.01% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 

Product Literature References

Overexpression, purification, and biochemical characterization of the extracellular human CD83 domain and generation of monoclonal antibodies: M. Lechmann, et al.; Protein Exp. Purif. 24, 445 (2002), Abstract;
The extracellular domain of CD83 inhibits dendritic cell-mediated T cell stimulation and binds to a ligand on dendritic cells: M. Lechmann, et al.; J. Exp. Med. 194, 1813 (2001), Abstract; Full Text

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