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 United States

CD83 (human), mAb (4B5)

 
ALX-805-044-C050 50 µg 176.00 USD
 

Product Specification

Concentration:1.7mg/ml
 
Formulation:Liquid. Protein G purified antibody in PBS containing 0.01% sodium azide.
 
Clone:4B5
 
Isotype:Rat IgG2a
 
Immunogen:Recombinant human CD83 (extracellular domain).
 
Specificity:Recognizes human CD83. Deglycosylated CD83 is only weakly recognized.
 
Application:Flow Cytometry
Western Blot
Note: NOT inhibitory to DC mediated T cell stimulation in mixed lymphocyte reactions.
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Handling:Do not freeze/thaw.
 

Product Literature References

Overexpression, purification, and biochemical characterization of the extracellular human CD83 domain and generation of monoclonal antibodies: M. Lechmann, et al.; Protein Exp. Purif. 24, 445 (2002), Abstract;
The extracellular domain of CD83 inhibits dendritic cell-mediated T cell stimulation and binds to a ligand on dendritic cells: M. Lechmann, et al.; J. Exp. Med. 194, 1813 (2001), Abstract; Full Text

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