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TRAIL-R2 (human) monoclonal antibody (DJR2-2)

 
ALX-804-913-0100 100 µg 205.00 USD
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Product Specification

Alternative Name:TRAIL receptor 2, DR5, Death receptor 5, KILLER, CD262, Trick2, Ly98, TNFRSF10B, TNF-related apoptosis-inducing ligand receptor 2, Tumor necrosis factor receptor superfamily member 10B
 
Clone:DJR2-2
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant human TRAIL-R2 extracellular domain IgG1 Fc fusion protein.
 
UniProt ID:O14763
 
Gene/Protein Identifier:8795 (Entrez GeneID)
 
Species reactivity:Human
 
Applications:Flow Cytometry, IHC (PS)
 
Purity Detail:Affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 0.09% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:DR5 is a 55kDa member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.
 

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