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TRAIL-R3 (human) monoclonal antibody (DJR3)

 
ALX-804-908-0100 100 µg 205.00 USD
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Product Specification

Alternative Name:TRAIL receptor 3, DcR1, Death Receptor 1, TRID, CD263, TNFRSF 10C, TNF-related apoptosis-inducing ligand receptor 3, Tumor necrosis factor receptor superfamily member 10C
 
Clone:DJR3
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant human TRAIL-R3 extracellular domain IgG1 Fc fusion protein.
 
UniProt ID:O14798
 
Gene/Protein Identifier:8794 (Entrez GeneID)
 
Species reactivity:Human
 
Applications:Flow Cytometry
 
Purity Detail:Affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 0.09% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:DcR1 is a 65kDa GPI-anchored member of the TNFR superfamily (TNFRSF10C) also known as TRAIL-R3, TRID, CD263, and LIT. Although not expressed by most tumors, DcR1 is expressed at low levels on normal tissues, acting as a TRAIL decoy receptor, thus inhibiting apoptosis. DcR1 is termed a decoy receptor, as it does not have a functional death domain to induce apoptosis following TRAIL ligation.
 

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