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LTβR (mouse) monoclonal antibody (5G11)

 
ALX-804-903-0100 100 µg 253.00 USD
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Product Specification

Alternative Name:Lymphotoxin-β receptor, TNFRSF 3, Tumor necrosis factor receptor 2 related protein, Tumor necrosis factor C receptor, Tumor necrosis factor receptor superfamily member 3 [precursor]
 
Clone:5G11
 
Host:Rat
 
Isotype:IgG2a
 
Immunogen:Extracellular domain of mouse LTβR (lymphotoxin β receptor) expressed in E. coli.
 
UniProt ID:P50284
 
Gene/Protein Identifier:17000 (Entrez GeneID)
 
Species reactivity:Mouse
 
Applications:Flow Cytometry
 
Purity Detail:Affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 0.09% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis. LTβR is a type I transmembrane glycoprotein and member of the TNF receptor superfamily. It is a 61kDa receptor for the mouse LTα1β2 and LIGHT. Northern blot analysis of tissues from adult mice showed that expression levels of LTβR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. It was reported that LTβR is expressed on stromal cells, monocytes, and certain embryonic epithelial layers. LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis.
 
ALX-804-903 FC
Flow cytometry analysis of C57BL/6 bone marrow cells stained with purified LTβR (mouse), mAb (5G11) (Prod. No. ALX-804-903) conjugated to PE (Upper panel) or rat IgG2a isotype control PE (Lower panel) and Ly-6G/Ly-6C FITC.
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ALX-804-903 FC

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