| Alternative Name: | Lymphotoxin-β receptor, TNFRSF 3, Tumor necrosis factor receptor 2 related protein, Tumor necrosis factor C receptor, Tumor necrosis factor receptor superfamily member 3 [precursor] |
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| Clone: | 5G11 |
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| Host: | Rat |
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| Isotype: | IgG2a |
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| Immunogen: | Extracellular domain of mouse LTβR (lymphotoxin β receptor) expressed in E. coli. |
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| UniProt ID: | P50284 |
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| Gene/Protein Identifier: | 17000 (Entrez GeneID) |
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| Species reactivity: | Mouse
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| Applications: | Flow Cytometry
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| Purity Detail: | Affinity purified. |
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| Formulation: | Liquid. In PBS, pH 7.2, containing 0.09% sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Scientific Background: | LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis. LTβR is a type I transmembrane glycoprotein and member of the TNF receptor superfamily. It is a 61kDa receptor for the mouse LTα1β2 and LIGHT. Northern blot analysis of tissues from adult mice showed that expression levels of LTβR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. It was reported that LTβR is expressed on stromal cells, monocytes, and certain embryonic epithelial layers. LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis. |
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| Regulatory Status: | RUO - Research Use Only |
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