Chemerin, mAb (Tigy-2)



ALX-804-869-C100	100 µg	200.00 USD

Product Specification

Alternative Name:	RARRES2, Retinoic acid receptor responder protein 2, TIG2, Tazarotene-induced gene 2 protein, RAR-responsive protein

Concentration:	1mg/ml

Purity Detail:	Protein G-affinity purified.

Purity:	≥95% (SDS-PAGE)

Formulation:	Liquid. In PBS containing 0.02% sodium azide.

Clone:	Tigy-2

Isotype:	Mouse IgG2b

Immunogen:	Recombinant rat chemerin (aa 23-157).

Source/Host:	Purified from concentrated hybridoma tissue culture supernatant.

Specificity:	Recognizes human and rat chemerin.

Application:	ELISA Western blot (1:1'000)

Short Term Storage:	+4°C

Long Term Storage:	-20°C

Use/Stability:	Stable for at least 1 year after receipt when stored at -20°C.

Handling:	After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Miscellaneous/General:	Chemerin (tazarotene-induced gene 2; TIG2) is a chemotactic agent that was identified as the ligand for the orphan G protein-coupled receptor ChemR23. Recently, chemerin has been shown to be expressed abundantly in adipose tissue and to function as an adipokine [1, 2]. Chemerin potentiates insulin-stimulated glucose uptake and regulates adipogenesis and adipocyte metabolism [1].

General Literature References

Chemerin is a novel adipokine associated with obesity and metabolic syndrome: K. Bozaoglu, et al.; Endocrinology 148, 4687 (2007), Abstract;

Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism: K.B. Goralski, et al.; J. Biol. Chem. 282, 28175 (2007), Abstract; Full Text