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ILEI monoclonal antibody (Delphy-1) (biotin conjugate)

 
ALX-804-857B-C100 100 µg Biotin 378.00 USD
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Product Specification

Alternative Name:Interleukin-like EMT inducer, FAM3C
 
Clone:Delphy-1
 
Host:Mouse
 
Isotype:IgG2a
 
Immunogen:Recombinant human ILEI (aa 42-227).
 
UniProt ID:Q92520
 
Source:Purified from concentrated hybridoma tissue culture supernatant.
 
Species reactivity:Human, Mouse
 
Applications:ELISA, WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G-affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored as recommended.
 
Handling:Do not freeze. Protect from light.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Long Term Storage:+4°C
 
Scientific Background:In 2006, T. Waerner, et al. characterized ILEI as a key player in both epithelial to mesenchymal transition and late-stage carcinoma progression. EMT is a process that involves changes in gene expression, cytoskeleton organization, cell adhesion, and extracellular matrix composition. This process is important during tissue formation and organogenesis, but also during cancer progression, metastasis and chronic inflammation. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer.
 

General Literature References

ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells: T. Waerner, et al.; Cancer Cell 10, 227 (2006), Abstract;
Cloning, expression, and initial characterization of a novel cytokine-like gene family: Y. Zhu, et al.; Genomics 80, 144 (2002), Abstract;

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ILEI monoclonal antibody (Delphy-1) 

Purified from concentrated hybridoma tissue culture supernatant., ELISA, IP, WB | Print as PDF
 
ALX-804-857-C100 100 µg 313.00 USD
Do you need bulk/larger quantities?
 

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