Omentin 1, mAb (Saly-2)



ALX-804-852-C100	100 µg	324.00 USD

Product Specification

Alternative Name:	Intelectin-1, Intestinal lactoferrin receptor, Galactofuranose-binding lectin, Endothelial lectin HL-1

Concentration:	1mg/ml

Purity Detail:	Protein G-affinity purified.

Purity:	≥95% (SDS-PAGE)

Formulation:	Liquid. In PBS containing 0.02% sodium azide.

Clone:	Saly-2

Isotype:	Mouse IgG2a

Immunogen:	Recombinant human omentin 1 (intelectin-1) (aa 17-231).

Source/Host:	Purified from concentrated hybridoma tissue cell culture supernatant.

Specificity:	Recognizes human omentin 1 and rat omentin. Cross-reacts with human omentin 2.

Application:	ELISA (detection) Western Blot (1:1'000)

Short Term Storage:	+4°C

Long Term Storage:	-20°C

Use/Stability:	Stable for at least 1 year after receipt when stored at -20°C.

Handling:	Avoid freeze/thaw cycles.

Miscellaneous/General:	Omentin 1 (also named intelectin-1, endothelial lectin HL-1 and intestinal lactoferrin receptor) has been identified as a visceral fat (or omental fat) depot-specific adipokine. Omentin 1 is a secreted protein of ~38 kDa containing a fibrinogen-related domain. Omentin 1 is highly expressed in the omental fat, and much less in intestine, lung and heart. Addition of recombinant omentin in vitro did not affect basal, but enhanced insulin-stimulated glucose uptake in subcutaneous as well as in omental human adipocytes. Omentin 1 triggers AKT signalling in the absence of insulin.

General Literature References

Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action: R.Z. Yang, et al.; Am. J. Physiol. Endocrinol. Metab. 290, E1253 (2006), Abstract;