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CTRP2 (mouse) monoclonal antibody (Didoo-1)

 
ALX-804-834-C100 100 µg 300.00 USD
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Product Specification

Alternative Name:Complement C1q tumor necrosis factor-related protein 2, C1qTNF2
 
Clone:Didoo-1
 
Host:Mouse
 
Isotype:IgG2b
 
Immunogen:Recombinant mouse CTRP2 (C1q tumor necrosis factor-α-related protein 2) (aa 26-260).
 
UniProt ID:Q9D8U4
 
Source:Purified from concentrated hybridoma tissue culture supernatant.
 
Species reactivity:Mouse
 
Applications:ELISA, IP, WB
 
Recommended Dilutions/Conditions:Immunoprecipitation (1:200)
Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
 
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Scientific Background:Adiponectin is involved in controlling the whole-body metabolism, particularly by increasing insulin sensitivity in muscle and liver, and by increasing fatty acid oxidation in muscle. CTRP2 belongs to a highly conserved family of adiponectin paralogs designated as C1q tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. CTRP2 (mouse) has been reported to rapidly induce phosphorylation of AMP-activated protein kinase, acetyl-CoA carboxylase, and mitogen-activated protein kinase in C2C12 myotubes, which resulted in increased glycogen accumulation and fatty acid oxidation.
 
804-834
Figure: Detection of mouse CTRP2 with MAb to CTRP2 (Didoo-1) (Prod. No. ALX-804-834) by Western blot. Method: Cell extracts (5x105) from HEK 293T( lane1) or HEK293wt transfected with a plasmid coding for mouse CTRP2 (lane 2) were resolved by SDS-PAGE under reducing conditions, transferred to nitrocellulose and incubated with the MAb to CTRP2 (Didoo-1) (1:1’000) for 2 hours, followed by incubation with HRP-coupled anti-mouse secondary antibody (1:4’000).
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804-834

General Literature References

A family of Acrp30/adiponectin structural and functional paralogs: G.W. Wong, et al.; PNAS 101, 10302 (2004), Abstract;

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