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RANKL (human) monoclonal antibody (Ranky-1)

 
ALX-804-830-C100 100 µg 345.00 USD
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Product Specification

Alternative Name:ODF, TRANCE, OPGL, TNFSF 11, CD254
 
Clone:Ranky-1
 
Host:Rat
 
Isotype:IgG1
 
Immunogen:Recombinant human soluble RANKL extracellular domain (aa 151-316) (Prod. No. ALX-522-012).
 
UniProt ID:O14788
 
Source:Purified from concentrated hybridoma tissue culture supernatant.
 
Species reactivity:Human
 
Applications:ELISA, IHC (PS), WB
 
Recommended Dilutions/Conditions:ELISA (capture)
Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Does not work for Flow Cytometry or Immunoprecipitation. Does not block RANK-RANKL interaction.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
804-830
Figure: Immunohistochemical staining of endogenous human RANKL in different human tissues (paraffin sections) using MAb to RANKL (human)(Ranky-1) (Prod. No. ALX-804-830). Method: Different human tissues (A: Duodenum; B: Small intestine) were stained with MAb to RANKL (human) (Ranky-1) by standard immunohistochemistry. Pictures courtesy of Human Protein Atlas (www.proteinatlas.org).
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804-830

General Literature References

The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling: S. Theoleyre, et al.; Cytokine Growth Factor Rev. 15, 457 (2004), Abstract;

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