BCMA (mouse), mAb (Vicky-2)



ALX-804-826-C100	100 µg	330.00 USD

Product Specification

Alternative Name:	B cell maturation protein, TNFRSF 17, CD269

Concentration:	1mg/ml

Purity Detail:	Protein G-affinity purified.

Formulation:	Liquid. In PBS containing 0.02% sodium azide.

Clone:	Vicky-2

Isotype:	Rat IgG2a

Immunogen:	Recombinant mouse BCMA extracellular domain (aa 1-46) (Prod. No. ALX-522-079).

Source/Host:	Purified from concentrated hybridoma tissue culture supernatant.

Specificity:	Recognizes mouse BCMA. Does not cross-react with human BCMA.

Application:	Immunoprecipitation (1:200) Flow Cytometry (1:1’000) Western Blot (1:1’000) Functional Application (blocks binding of BAFF to mouse BCMA)

Short Term Storage:	+4°C

Use/Stability:	Stable for at least 1 year after receipt when stored at -20°C.

Handling:	Avoid freeze/thaw cycles. For long-term storage, aliquot and freeze at -20°C.

Western blot analysis of BCMA: Lane 1: MW marker, Lane 2: Mouse BCMA Recombinant Protein.

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Product Literature References

APRIL facilitates viral-induced erythroleukemia but is dispensable for T cell immunity and lymphomagenesis: G. Hardenberg, et al.; J. Leukoc. Biol. 84, 380 (2008), Abstract; Full Text

General Literature References

TACI and BAFF-R mediate isotype switching in B cells: E. Castigli, et al.; J. Exp. Med. 201, 35 (2005), Abstract;

B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation: S. Shulga-Morskaya, et al.; J. Immunol. 173, 2331 (2004), Abstract;