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CD3 (human) monoclonal antibody (TR66)

 
ALX-804-822-C100 100 µg 226.00 USD
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Product Specification

Clone:TR66
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Cloned human helper T cell line.
 
UniProt ID:P09693 (γ chain), P04234 (δ chain), P07766 (ε chain), P20963 (ζ chain)
 
Source:Purified from concentrated hybridoma tissue culture supernatant.
 
Species reactivity:Human
 
Specificity:Recognizes the ε-chain of CD3.
 
Applications:Flow Cytometry, ICC, IP, FUNC
 
Application Notes:Detects endogenous protein by FC, ICC and IP.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
 
Handling:For long term storage, aliquot and freeze at -20°C. Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 

Product Literature References

T cell fitness determined by signal strength: A.V. Gett, et al.; Nat. Immunol. 4, 355 (2003), Abstract;
CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation: O. Gaide, et al.; Nat. Immunol. 3, 836 (2002), Abstract;
T lymphocyte costimulation mediated by reorganization of membrane microdomains: A. Viola, et al.; Science 283, 680 (1999), Abstract;
FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation: T. Kataoka, et al.; J. Immunol. 161, 3936 (1998), Abstract; Full Text
The use of hybrid hybridomas to target human cytotoxic T lymphocytes: A. Lanzavecchia & D. Scheidegger; Eur. J. Immunol. 17, 105 (1987), Abstract;

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