Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Promyelocytic leukemia protein (mouse) monoclonal antibody (36-1-104)

 
ALX-804-816-C100 100 µg 356.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:PML
 
Clone:36-1-104
 
Host:Mouse
 
Isotype:IgG2b
 
Immunogen:Recombinant mouse PML (promyelocytic leukemia protein) (aa 1-581).
 
UniProt ID:Q60953
 
Source:Purified from concentrated hybridoma tissue culture supernatant.
 
Species reactivity:Mouse
 
Specificity:Detects endogenous protein by ICC, IP and WB.
 
Crossreactivity:Does not cross-react with human PML.
 
Applications:ICC, IP, WB
EMSA
 
Recommended Dilutions/Conditions:Immunocytochemistry (1:100)
Western Blot (1:500-1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Formulation:Liquid. Purified antibody in PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least one year after receipt if stored at -20°C.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 

Please mouse over

Product Literature References

Identification of a tumour suppressor network opposing nuclear Akt function: L.C. Trotman, et al.; Nature 441, 523 (2006), Abstract; Full Text
PML is a direct p53 target that modulates p53 effector functions: E. de Stanchina, et al.; Mol. Cell 13, 523 (2004), Abstract;
PML regulates p53 stability by sequestering Mdm2 to the nucleolus: R. Bernardi, et al.; Nat. Cell Biol. 6, 665 (2004), Abstract;

General Literature References

PML nuclear bodies and apoptosis: Y. Takahashi, et al.; Oncogene 23, 2819 (2004), Abstract;
PML regulates p53 stability by sequestering Mdm2 to the nucleolus: R. Bernardi, et al.; Nat. Cell Biol. 6, 665 (2004), Abstract;
The role of PML in tumor suppression: P. Salomoni and P.P. Pandolfi; Cell 108, 165 (2002), Abstract;
PML is induced by oncogenic ras and promotes premature senescence: G. Ferbeyre, et al.; Genes Dev. 14, 2015 (2000), Abstract;

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
Promyelocytic leukemia protein
By biological activity:
Promyelocytic leukemia protein Monoclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,