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BAFF-R (human) monoclonal antibody (11C1)

 
ALX-804-807-C100 100 µg 334.00 USD
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Product Specification

Alternative Name:BR3, BlySR3, TNFRSF 13C, CD268
 
Clone:11C1
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Mouse B cell lymphoma L1.2 cells expressing human BAFF-R.
 
UniProt ID:Q96RJ3
 
Source:Purified from concentrated mouse hybridoma tissue culture supernatant.
 
Species reactivity:Human
 
Applications:Flow Cytometry, IHC (FS), IHC (PS)
 
Application Notes:Works on endogenous.
 
Purity Detail:Protein G-affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 6 months after receipt when stored as recommended.
 
Handling:For long term storage, aliquot and freeze at -20°C. Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
804-807
Figure 1: Detection of endogenous BAFF-R in a human palatine tonsil paraffin section stained with the MAb to BAFF-R (human) (11C1) (Prod. No. ALX-804-807). An intense staining of B cells follicles and weaker staining of germinal center is observed (200x).
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804-807

Product Literature References

Autoantibody-producing RP105(-) B cells, from patients with systemic lupus erythematosus, showed more preferential expression of BCMA compared with BAFF-R than normal subjects: S. Koarada, et al.; Rheumatology (Oxford) 49, 662 (2010), Abstract; Full Text
B cell-activating factor belonging to the TNF family (BAFF)-R Is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells: L.G. Ng, et al.; J. Immunol. 173, 807 (2004), Abstract;

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