ACE2 (human), mAb (AC18F)



ALX-804-715-C050	50 µg	226.00 USD

ALX-804-715-C100	100 µg	278.00 USD

Product Specification

Alternative Name:	Angiotensin-converting enzyme 2, SARS receptor

Concentration:	1mg/ml

Formulation:	Liquid. In PBS, pH 7.4. Contains no preservatives.

Clone:	AC18F

Isotype:	Mouse IgG1

Immunogen:	Recombinant human ACE2 (angiotensin-converting enzyme 2).

Specificity:	Recognizes human ACE2.

Application:	ELISA (direct and indirect: 1:2’000-1:10’000) Flow Cytometry Western Blot (1:2’000-1:10’000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature) Optimal conditions must be determined individually for each application.

Short Term Storage:	+4°C

Long Term Storage:	-20°C

Handling:	After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Figure 1: Western blot analysis of ACE2 using MAb to ACE2 (human) (AC18F) (Prod. No. ALX-804-715) at 1: 2’000 dilution. 1. Human ACE2:Fc (human) (recombinant) (Prod. No. ALX-201-330). 2. Human recombinant FLAG^®-tagged ACE2 (Ecto domain) fusion protein. (Prod. No. ALX-201-356).3. Other Fc-fusion protein (human GITR-Fc).

Figure 2: HepG2 cells were stained significantly by MAb to ACE2 (human) (AC18F) (Prod. No. ALX-804-715).

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Product Literature References

Co-localization of angiotensin-converting enzyme 2-, octomer-4- and CD34 positive cells in rabbit atherosclerotic plaques: A. Zulli, et al.; Exp. Physiol. 93, 564 (2008), Abstract;