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Bcl-XL monoclonal antibody (1C2)

 
ALX-804-660-C100 100 µg 313.00 USD
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Product Specification

Alternative Name:BCL2L1
 
Clone:1C2
 
Host:Rat
 
Isotype:IgG2a κ
 
Immunogen:Recombinant mouse Bcl-XL (aa 1-209).
 
UniProt ID:Q64373
 
Species reactivity:Human, Mouse
 
Applications:ELISA, Flow Cytometry, IP, WB
 
Purity Detail:Protein G-affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 

Product Literature References

Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak: R.T. Uren, et al.; J. Cell Biol. 177, 277 (2007), Abstract;
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins: S.N. Willis, et al.; Genes Dev. 19, 1294 (2005), Abstract; Full Text

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