Bcl-X_L, mAb (1C2)



ALX-804-660-C100	100 µg	276.00 USD

Product Specification

Alternative Name:	BCL2L1

Concentration:	1mg/ml

Purity Detail:	Protein G-affinity purified.

Formulation:	Liquid. In PBS containing 0.02% sodium azide.

Clone:	1C2

Isotype:	Rat IgG2_aκ

Immunogen:	Recombinant mouse Bcl-X_L (aa 1-209).

Specificity:	Recognizes human and mouse Bcl-X_L.

Application:	ELISA Flow Cytometry Immunoprecipitation Western Blot

Short Term Storage:	+4°C

Long Term Storage:	-20°C

Handling:	Avoid freeze/thaw cycles.

Product Literature References

Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak: R.T. Uren, et al.; J. Cell Biol. 177, 277 (2007), Abstract;

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins: S.N. Willis, et al.; Genes Dev. 19, 1294 (2005), Abstract; Full Text