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Toll-like receptor 5 monoclonal antibody (85B152.5) (R-PE conjugate)

ALX-804-597R-C100 100 µg R-PE 466.00 USD
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Product Specification

Alternative Name:TLR5, Toll/Interleukin-1 receptor-like gene 3, TIL3
Immunogen:Synthetic peptide corresponding to a portion of human TLR5 (Toll-like receptor 5).
UniProt ID:O60602
Species reactivity:Human, Mouse
Applications:Flow Cytometry
Application Notes:Flow Cytometry: Suitable for cell surface and intracellular FC.
Positive Control:Ramos cells can be used as positive control.
Purity Detail:Protein G-affinity purified.
Formulation:Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
Use/Stability:Stable for 6 months when stored at +4°C.
Handling:Do not freeze. Protect from light.
Shipping:Shipped on Blue Ice
Short Term Storage:+4°C
Long Term Storage:+4°C
Figure: Intracellular FACS analysis of TLR5 in 106 ThP1 cells using 5µg of MAb to Toll-like Receptor 5 (85B152.5) (R-PE) (Prod. No. ALX-804-597R). The shaded histogram represents ThP1 cells alone, green represents isotype control, and pink represents TLR5 antibody.
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Product Literature References

Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils: C.K. Wong, et al.; Am. J. Respir. Cell Mol. Biol. 37, 85 (2007), Abstract;
Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk: E. LeBouder, et al.; J. Immunol. 176, 3742 (2006), Abstract; Full Text
Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis: A. Mansson, et al.; Respir. Res. 7, 36 (2006), Abstract; Full Text
Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells: N.K. Crellin, et al.; J. Immunol. 175, 8051 (2005), Abstract; Full Text

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