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LBP (mouse) monoclonal antibody (biG 33)

 
ALX-804-502-C100 100 µg 291.00 USD
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Product Specification

Alternative Name:Lipopolysaccharide binding protein
 
Clone:biG 33
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant mouse LBP (lipopolysaccharide binding protein) (in LBP knockout mouse).
 
UniProt ID:Q61805
 
Species reactivity:Mouse
 
Crossreactivity:Cross-reacts weakly with rat LBP.
 
Applications:ELISA, WB, FUNC
 
Recommended Dilutions/Conditions:ELISA, Western Blot, Functional Application (Inhibits binding of LPS to membrane bound CD14)
 
Application Notes:Functional Application: inhibits binding of LPS to membrane bound CD14.
 
Purity Detail:Protein-G affinity purified.
 
Endotoxin Content:<0.1ng/ml (LAL-test Charles River)
 
Formulation:Lyophilized. Contains PBS.
 
Reconstitution:Reconstitute with 40µl distilled water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Technical Info/Product Notes:Binding titer at mouse LBP-ELISA: 1:50'000.
Inhibits LPS-binding (0.5µg/ml) to CD14+ CHO cells (2x106/ml) up to 1:1'000, total inhibition is 1:5.
 

Product Literature References

Implications for a general role of LPS-binding proteins (CD14, LBP) in combating bacterial infections: C. Schütt, et al.; J. Endotoxin Res. 5, 75 (1999), Full Text

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