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Toll-like receptor 3 (human) monoclonal antibody (TLR3.7)

 
ALX-804-474-C050 50 µg 226.00 USD
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Product Specification

Alternative Name:TLR3, CD283
 
Clone:TLR3.7
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant human TLR3 (Toll-like receptor 3).
 
UniProt ID:O15455
 
Species reactivity:Human
 
Applications:Flow Cytometry, ICC, IP, FUNC
 
Application Notes:Functional Application: blocks double-stranded RNA-mediated signalling
 
Formulation:Liquid. Purified antibody in PBS containing 10% glycerol. Does not contain any preservatives.
 
Use/Stability:Stable for at least 1 year after receipt when stored as recommended.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
804-474 FUNC
Figure: Clone TLR3.7 inhibits dsRNA-induced IFN-b production by MRC-5 cells.
804-474 IP
Figure: Immunoprecipitation of human TLR3 in transfectants with clone TLR3.7.
804-474 FC
Figure: FC with clone TLR3.7.
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804-474 FUNC 804-474 IP 804-474 FC

Product Literature References

Mechanism of up-regulation of human Toll-like receptor 3 secondary to infection of measles virus-attenuated strains: M. Tanabe, et al.; BBRC 311, 39 (2003), Abstract;
Subcellular localization of Toll-like receptor 3 in human dendritic cells: M. Matsumoto, et al.; J. Immunol. 171, 3154 (2003), Abstract;
Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling: M. Matsumoto, et al.; BBRC 293, 1364 (2002), Abstract;

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