Toll-like receptor 3 (human), mAb (TLR3.7)



ALX-804-474-C050	50 µg	220.00 USD

Product Specification

Alternative Name:	TLR3, CD283

Concentration:	0.2mg/ml.

Formulation:	Liquid. Purified antibody in PBS containing 10% glycerol. Does not contain any preservatives.

Clone:	TLR3.7

Isotype:	Mouse IgG1

Immunogen:	Recombinant human TLR3 (Toll-like receptor 3).

Specificity:	Recognizes human TLR3.

Application:	Flow Cytometry Immunocytochemistry Immunoprecipitation Functional Application (blocks double-stranded RNA-mediated signalling)

Long Term Storage:	-20°C

Use/Stability:	Stable for at least 1 year after receipt when stored as recommended.

Handling:	Avoid freeze/thaw cycles.

Figure: Clone TLR3.7 inhibits dsRNA-induced IFN-b production by MRC-5 cells.

Figure: Immunoprecipitation of human TLR3 in transfectants with clone TLR3.7.

Figure: FC with clone TLR3.7.

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Product Literature References

Mechanism of up-regulation of human Toll-like receptor 3 secondary to infection of measles virus-attenuated strains: M. Tanabe, et al.; BBRC 311, 39 (2003), Abstract;

Subcellular localization of Toll-like receptor 3 in human dendritic cells: M. Matsumoto, et al.; J. Immunol. 171, 3154 (2003), Abstract;

Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling: M. Matsumoto, et al.; BBRC 293, 1364 (2002), Abstract;