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HtrA2/Omi (human) monoclonal antibody (196C429)

 
ALX-804-427-C100 100 µg 323.00 USD
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Product Specification

Clone:196C429
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Synthetic peptide corresponding to aa 335-350 of human HtrA2/Omi.
 
UniProt ID:O43464
 
Species reactivity:Human
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Western Blot (2-3µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects bands of ~38kDa and ~50kDa by Western blot.
 
Purity Detail:Protein G-affinity purified.
 
Formulation:Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
804-427 1
Figure 1: Immunohistochemistry using MAb to HtrA2/Omi (human) (196C429) (Prod. No. ALX-804-427) shows cytoplasmic staining in stomach tumor tissue (A) and very weak staining in normal stomach tissue (B).
804-427
Figure 2: Western blot detection of Omi/HtrA2 in HL-60cell lysate. Two protein bands of approximate molecular weight of 50 and 38kDa was detected using ALX-804-427 at 2µg/ml dilution. The two bands may represent precursor and mature form of Omi/Htra2, respectively.
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804-427 1 804-427

Product Literature References

Apoptotic death concurrent with CD3 stimulation in primary human CD8+ T lymphocytes: a role for endogenous granzyme B: M. Laforge, et al.; J. Immunol. 176, 3966 (2006), Abstract;
X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia: X. Wang, et al.; Neurobiol. Dis. 16, 179 (2004), Abstract;
Immunohistochemical analysis of Omi/HtrA2 expression in stomach cancer: S.H. Lee, et al.; APMIS 111, 586 (2003), Abstract;

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