Product Details
Clone: | 6G12 |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Synthetic peptide corresponding to aa 1-43 of human β-amyloid conjugated to KLH. |
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UniProt ID: | P05067 |
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Species reactivity: | Human
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Crossreactivity: | Does not cross-react with β-amyloid (aa 1-40 or aa 1-42). |
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Applications: | ELISA, ICC, WB
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Recommended Dilutions/Conditions: | Immunocytochemistry (0.1-1µg/ml) Western Blot (1µg/ml for AP/BCIP/NBT (MTT) detection; 0.5µg/ml for HRPO/ECL detection) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Thiophilic adsorption and size exclusion chromatography purified. |
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Formulation: | Lyophilized from 1ml of 2x PBS containing 0.09% sodium azide, PEG, and sucrose. |
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Reconstitution: | Reconstitute with 1ml water (15 minutes at room temperature). |
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Use/Stability: | Stable at -80°C up to 1 year, at 4°C up to 3 months. |
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Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and freeze in liquid nitrogen. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Aβ43 is potently amyloidogenic, neurotoxic and abundant in vivo. |
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Regulatory Status: | RUO - Research Use Only |
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General Literature References
Potent amyloidogenicity and pathogenicity of Aβ43: T. Saito, et al.; Nat. Neurosci.
14, 1023 (2011),
Abstract;