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β-Amyloid (1-43) (human) monoclonal antibody (6G12)

 
ALX-804-413-C100 100 µg 410.00 USD
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Product Specification

Clone:6G12
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Synthetic peptide corresponding to aa 1-43 of human β-amyloid conjugated to KLH.
 
UniProt ID:P05067
 
Species reactivity:Human
 
Crossreactivity:Does not cross-react with β-amyloid (aa 1-40 or aa 1-42).
 
Applications:ELISA, ICC, WB
 
Recommended Dilutions/Conditions:Immunocytochemistry (0.1-1µg/ml)
Western Blot (1µg/ml for AP/BCIP/NBT (MTT) detection; 0.5µg/ml for HRPO/ECL detection)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Thiophilic adsorption and size exclusion chromatography purified.
 
Formulation:Lyophilized from 1ml of 2x PBS containing 0.09% sodium azide, PEG, and sucrose.
 
Reconstitution:Reconstitute with 1ml water (15 minutes at room temperature).
 
Use/Stability:Stable at -80°C up to 1 year, at 4°C up to 3 months.
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and freeze in liquid nitrogen.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Aβ43 is potently amyloidogenic, neurotoxic and abundant in vivo.
 

General Literature References

Potent amyloidogenicity and pathogenicity of Aβ43: T. Saito, et al.; Nat. Neurosci. 14, 1023 (2011), Abstract;

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