β-Amyloid (1-43) (human), mAb (6G12)

Purity Detail:	Purified from serum-free cell culture supernatant by subsequent thiophilic adsorption and size exclusion chromatography.

Formulation:	Lyophilized from 1ml 2x PBS, 0.09% sodium azide, PEG and sucrose.

Clone:	6G12

Isotype:	Mouse IgG1

Immunogen:	Synthetic peptide corresponding to aa 1-43 of human β-amyloid.

Reconstitution:	Reconstitute with 1ml distilled water (15 min., RT).

Specificity:	Recognizes human β-amyloid (aa 1-43). Does not cross-react with β-amyloid (aa 1-40 or aa 1-42).

Application:	Immunocytochemistry (0.1-1µg/ml) Western Blot (1µg/ml for AP/BCIP/NBT (MTT) detection; 0.5µg/ml for HRPO/ECL detection).

Long Term Storage:	-20°C

Use/Stability:	Reconstituted antibody is stable for 1 year when stored at -80°C. Thaw aliquots at +37°C. Thawed aliquots may be stored at +4°C for up to 3 months.

Handling:	After reconstitution, prepare aliquots and freeze in liquid nitrogen. Avoid freeze/thaw cycles.

Miscellaneous/General:	Aβ43 is potently amyloidogenic, neurotoxic and abundant in vivo.